Stocks making the biggest moves midday: Horizon Therapeutics, Capital One, RH, Home Depot and more

Check retired the companies making the biggest moves midday:

Horizon Therapeutics — Shares of the biotech steadfast fell much than 15% aft the Federal Trade Commission sued to artifact the company's acquisition by biopharmaceutical elephantine Amgen. The deal, worthy $27.8 billion, was meant to fortify Amgen's cause portfolio arsenic it faces respective patent expirations implicit the adjacent decennary for cardinal treatments.

Vodafone — U.S.-listed shares of the British telecommunications institution dropped 7% aft Vodafone announced plans to chopped 11,000 jobs. CEO Margherita Della Valle said the company's show "has not been bully enough" and Vodafone "must change."

Western Alliance Bancorp — Western Alliance shares jumped 3.6% aft Bank of America reinstated sum connected the banal with a bargain rating. Bank of America said it is assured successful the determination bank's concern model. The steadfast said that "WAL does not stock a ton successful presumption of concern exemplary and equilibrium expanse characteristics comparative to the 3 failed banks," noting its above-average ratio of insured deposits to full deposits. Shares are down 46% twelvemonth to date.

Capital One — Capital One's banal gained 2.4% a time aft securities filings revealed a new involvement successful the fiscal instauration from Warren Buffett's Berkshire Hathaway worthy much than $950 million. Regulatory documents besides showed Michael Burry's Scion Asset Management picked up immoderate shares during the archetypal quarter.

RH — Shares of the luxury furnishings retailer slid 7.5%. A regulatory filing posted precocious Monday showed that Warren Buffett's Berkshire Hathaway dumped its involvement past quarter. The Omaha-based conglomerate had owned 2.36 cardinal shares of RH astatine the extremity of 2022.

Alphabet — The banal added astir 3% successful midday trading. On Monday, Bill Ackman's Pershing Square Capital Management revealed successful a securities filing that it opened a caller presumption successful Alphabet totaling astir $1.1 billion during the archetypal quarter. Dan Loeb's Third Point besides built a sizeable stake successful the tech elephantine successful the archetypal quarter. 

Home Depot, Lowe's — Shares of location betterment retailers Home Depot and Lowe's mislaid 1.4% and 1% successful midday trading Tuesday. Home Depot reported the biggest gross miss successful much than 20 years earlier successful the day, posting $37.26 cardinal portion analysts forecasted by Refinitiv forecasted $38.28 billion. Lowe's volition study quarterly results connected May 23.

Expedia — The question booking tract relation saw its shares emergence 2.7% aft Gordon Haskett upgraded the stock to bargain from hold. The steadfast said concerns astir its tech stack migration are overblown and that it sees a tailwind from accepted lodging offerings. It besides highlighted the upcoming motorboat of its One Key program, which is expected to thrust aboriginal stock gains.

Seagen — Shares of the biotechnology institution shed 5%. On Monday, Daniel Welch, a manager astatine Seagen, disclosed the merchantability of 1,864 shares, a involvement worthy much than $370,000. Seagen and Pfizer besides filed paperwork for their projected merger to the Federal Trade Commission connected Friday, conscionable days earlier the FTC sued to artifact Amgen's acquisition of Horizon Therapeutics.

Sea Limited — The user net institution dropped 17% aft somewhat missing expectations for first-quarter revenue. The institution posted $3.04 billion, nether the $3.06 cardinal statement estimation of analysts polled by FactSet.

GE HealthCare — The medtech company's shares gained astir 3% aft Oppenheimer initiated sum with an outperform rating connected Monday. The steadfast said GE HealthCare is well-positioned to payment from an aging colonisation and emergence successful cases of chronic diseases. GE HealthCare separated from genitor company General Electric earlier successful 2023 and began publically trading connected the Nasdaq Jan. 4.

Etsy — The banal sank much than 5% aft Morgan Stanley chopped its terms people to $74 per stock from $79, implying 24% downside from Monday's close. The Wall Street steadfast said it sees slower maturation up for Etsy.

—CNBC's Yun Li, Tanaya Macheel, Alex Harring, Samantha Subin, Hukyung Kim, Brian Evans, Sarah Min and Michael Bloom contributed reporting.